化合物mTOR inhibitor-1 T5338

Product Introduction
Bioactivity


英文名: mTOR inhibitor-1

描述: mTOR inhibitor-1是一种新型 ATP 竞争性 mTOR 抑制剂，可抑制细胞生长和增殖，诱导自噬。

体外活性: The addition of C-4 (mTOR inhibitor-1, 0~12.8 μg/ml) directly decreases the level of activated mTOR (p-mTORser2448) which is phosphorylated at Ser2448. The proliferation of A549 cells is strongly inhibited by C-4, and the inhibitory effect is time- and dose314 dependent. The IC50 of C-4 at 24 h is calculated as 3.176 μM.

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 70 mg/mL (192.72 mM)


关键字: mTOR inhibitor1 | Mammalian target of Rapamycin | mTOR | inhibit | mTOR inhibitor 1 | Inhibitor | mTOR inhibitor-1 | Autophagy

相关产品: hSMG-1 inhibitor 11j | Hirsutenone | Hederacolchiside A1 | Azemiglitazone | AZ20 | GSK-25 | L-Leucine | mTOR inhibitor-3 | Rotundic acid | Thioether-cyclized helix B peptide, CHBP TFA

相关库: HIF-1 Signaling Pathway Compound Library | Glycometabolism Compound Library | Anti-Liver Cancer Compound Library | Pyroptosis Compound Library | Anti-Cancer Compound Library | Kinase Inhibitor Library | Inhibitor Library | Anti-Obesity Compound Library | Glycolysis Compound Library | Bioactive Compound Library

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途