L-硒代蛋氨酸 T5372

Product Introduction
Bioactivity


英文名: L-SelenoMethionine

描述: L-SelenoMethionine (L-(+)-Selenomethionine) 是 Selenomethionine 的 L-异构体，是硒的主要天然食物形式。它是一种癌症化学预防剂，可以增加谷胱甘肽过氧化物酶的表达，还可以通过饮食补充降低癌症的发生率并诱导癌细胞凋亡。

体外活性: At 5 μM, L-selenomethionine selectively induces apoptosis in LNCaP prostate cancer cells without affecting non-cancerous cells [1]. c-Myc, cyclin C, proliferating cell nuclear antigen, cyclin-dependent kinase (cdk)1, cdk2, cdk4, cyclin B and cyclin D2 mRNA levels were lower in selenium-deficient cells than in the cells supplemented with 0.25 micromol/L selenomethionine. The phosphorylation state of total cellular protein was higher (57%) in selenium-supplemented cells than in selenium-deficient cells [2].

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : < 1mg/ml (insoluble）
H2O : 30 mg/mL(152.97 mM)


关键字: selenium | peroxidase | glutathione | dietary | Apoptosis | cancer | L SelenoMethionine | LSelenoMethionine | inhibit | chemopreventive | Endogenous Metabolite | Inhibitor | L-SelenoMethionine

相关产品: AK301 | APE1-IN-2 | Taurochenodeoxycholic Acid | PG-11047 2HCl | Tubastatin A | Cyclovirobuxine D | LRRK2-IN-1 | Niraparib hydrochloride | Limonin | m-3M3FBS

相关库: FDA-Approved Drug Library | Drug Repurposing Compound Library | Oxidation-Reduction Compound Library | Anti-Cancer Drug Library | Clinical Compound Library | Bioactive Compounds Library Max | Anti-Cancer Clinical Compound Library | Anti-Cancer Active Compound Library | Anti-Cancer Approved Drug Library | RO5 Drug-like Natural Product Library

L-硒代蛋氨酸 T5372信息由TargetMol中国为您提供，如您想了解更多关于L-硒代蛋氨酸 T5372报价、型号、参数等信息，欢迎来电或留言咨询。

注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途