化合物AK-1 T5618
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
25 mg | 330461-64-8 | ¥1,330.00 | 询底价 |
2 mg | 330461-64-8 | ¥258.00 | 询底价 |
50 mg | 330461-64-8 | ¥1,980.00 | 询底价 |
1 mL | 330461-64-8 | ¥490.00 | 询底价 |
100 mg | 330461-64-8 | ¥3,160.00 | 询底价 |
5 mg | 330461-64-8 | ¥413.00 | 询底价 |
10 mg | 330461-64-8 | ¥663.00 | 询底价 |
Product Introduction
Bioactivity
英文名: AK-1
描述: AK-1是一种特异性有效和细胞可渗透的SIRT2抑制剂,其IC50值为 12.5 μM。它可防止阿尔茨海默病模型中的海马神经退行性变并诱导结肠癌细胞中的细胞周期停滞。
体外活性: AK-1 induces the formation of α-synuclein aggregates in H4 neuroglioma cells expressing α-synuclein and synphilin-1.AK-1 (5 μM) decreases total cholesterol levels in Neuro2a and primary rat striatal neurons, as well as in hippocampal slice cultures[1].
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO : 50 mg/mL (123.93 mM)
关键字: inhibit | AK 1 | AK1 | Inhibitor | AK-1 | Sirtuin
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途