蒜氨酸 T5764
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
25 mg | 556-27-4 | ¥2,760.00 | 询底价 |
10 mg | 556-27-4 | ¥1,670.00 | 询底价 |
1 mg | 556-27-4 | ¥347.00 | 询底价 |
1 mL | 556-27-4 | ¥739.00 | 询底价 |
50 mg | 556-27-4 | ¥3,870.00 | 询底价 |
100 mg | 556-27-4 | ¥5,420.00 | 询底价 |
5 mg | 556-27-4 | ¥923.00 | 询底价 |
Product Introduction
Bioactivity
英文名: Alliin
描述: Alliin ((S)-3-(Allylsulphinyl)-L-alanine) 是一种从大蒜中提取的亚砜化合物,具有口服活性,表现出降血糖、抗氧化和抗炎特性。
体内活性: LPS-induced ALI was induced in BALB/c mice by intranasal instillation of LPS.?Alliin was administered intraperitoneally to mice 1 h after LPS treatment.?Alliin markedly inhibited lung myeloperoxidase (MPO) activity and wet/dry (W/D) ratio induced by LPS.?Alliin also inhibited TNF-α and IL-1β in the bronchoalveolar lavage fluid (BALF) induced by LPS.?Furthermore, LPS-induced lung pathological injury was attenuated by treatment of alliin.?LPS-induced NF-κB activation was significantly inhibited by alliin.?In addition, the expression of peroxisome proliferator-activated receptor γ (PPARγ) was up-regulated by treatment of alliin.?Taken together,Alliin protected against LPS-induced ALI by activating PPARγ, which subsequently inhibited LPS-induced NF-κB activation and inflammatory response.
存储条件: store at low temperature,keep away from direct sunlightPowder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO : 3 mg/mL (16.92 mM)
关键字: Alliin | inhibit | Inhibitor | 3-(Allylsulphinyl)-L-alanine
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相关库: Anti-Neurodegenerative Disease Compound Library | Anti-Inflammatory Traditional Chinese Medicine Compound Library | Anti-Liver Cancer Compound Library | Oxidation-Reduction Compound Library | NF-κB Signaling Compound Library | Anti-Diabetic Compound Library | Traditional Chinese Medicine Monomer Library | RO5 Drug-like Natural Product Library | Stem Cell Differentiation Compound Library | Natural Product Library
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途