化合物 BPH-1086 T60300
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
100 mg | 1226901-43-4 | ¥17,500.00 | 询底价 |
25 mg | 1226901-43-4 | ¥10,600.00 | 询底价 |
50 mg | 1226901-43-4 | ¥13,800.00 | 询底价 |
Product Introduction
Bioactivity
英文名: BPH-1086
描述: BPH-1086 (compound 10) 是一种IspH 抑制剂。IspH 结构域通过与核糖体蛋白 (RPS1) 融合,能够结合 mRNA 或形成细菌核糖体。
体外活性: IspH (LytB) is the last enzyme in the nonmevalonate pathway. The IspH domains can be fused to either the ribosomal protein S1 (RPS1), IspH–RPS1 binds to mRNA or forms part of the bacterial ribosome [1] [2]. IspH–RPS1 proteins are present in anaerobes found in the human gut and some, such as Clostridium botulinum, C. tetani and Fusobacterium nucleatum, are pathogens [2]. IspH inhibitor will therefore kill bacteria directly, as with other antibiotics, but will also kill persistent bacteria by microptosis [3].
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途