化合物 As-358 T60623

Product Introduction
Bioactivity


英文名: As-358

描述: As-358 对埃博拉病毒 (IC50 = 47.5 μM) 和马尔堡病毒 (IC50 = 3.7 μM) 具有抑制作用。

体外活性: As-358 (compound 3b) (0-500 μM; 10 days) exhibits inhibitory activities against EBOV and MARV [1]. As-358 (0-100 μM; 48 hours) can inhibit WT-EboV-GP and mutant D522A-EboV-GP, with IC 50 s of 1.7 and 2.2 μM, respectively [1]. Cell Proliferation Assay Cell Line: Vero (infected with EBOV and MARV) [1] Concentration: 0-500 μM Incubation Time: 10 days Result: Exhibited inhibitory activities against EBOV and MARV, with IC 50 s of 47.5 ± 8.2 μM and 3.7 ± 1.7 μM, SI values of 9 and 118, respectively.

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途