化合物 Dichlorphenamide disodium T61216
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
100 mg | 76382-13-3 | ¥17,500.00 | 询底价 |
50 mg | 76382-13-3 | ¥13,800.00 | 询底价 |
25 mg | 76382-13-3 | ¥10,600.00 | 询底价 |
Product Introduction
Bioactivity
英文名: Dichlorphenamide disodium
描述: Dichlorphenamide disodium is a specific, orally active carbonic anhydrase inhibitor. It effectively reduces intraocular pressure by impeding the secretion of aqueous humor. Notably, dichlorphenamide disodium holds potential for glaucoma research [1].
体内活性: Dichlorphenamide disodium can reduce IOP locally in male albino rabbits [1]. Animal Model: Male albino rabbits (approximately 2.5 kg) [1] Dosage: 50 μL 10% aqueous solutions of dichlorphenamide sodium or 2 mg/kg, 6 mg/kg Administration: Eye drop of 50 μL or Oral gavage of 2 mg/kg or 6 mg/kg,5 hours Result: Showed significant decrease in IOP at 30 min by instilling into eyes and decrease in IOP only at 1 h by orally after drug administration. And demonstrated that drug levels were significantly higher in the iris ciliary body and lower in the serum by instilling compared to oral administration.
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途