化合物RGFP966 (E-isomer) T6286

Product Introduction
Bioactivity


英文名: RGFP966 (E-isomer)

描述: RGFP966 是一种 HDAC3 抑制剂，IC50 为 0.08 μM，比其他 HDAC 选择性高 200 倍以上。

体外活性: In mammals, halofuginone at 10 ng/ml down-regulates Smad3, blocking TGF-β signaling and preventing both the differentiation of fibroblasts to myofibroblasts and the transitioning of epithelial cells to mesenchymal cells[2].

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: Ethanol : < 1 mg/mL (insoluble or slightly soluble)
H2O : < 1 mg/mL (insoluble or slightly soluble)
DMSO : 67 mg/mL (184.9 mM)


关键字: E-isomer | RGFP-966 | RGFP 966 | RGFP966

相关产品: HDAC6-IN-19 | J27644 | SantacruzaMate A | Splitomicin | Givinostat hydrochloride | HDAC6-IN-22 | BML-210 | Panobinostat | Fimepinostat | HDAC6-IN-25

相关库: Anti-Breast Cancer Compound Library | NF-κB Signaling Compound Library | Bioactive Compounds Library Max | Inhibitor Library | Epigenetics Compound Library | Highly Selective Inhibitor Library | DNA Damage & Repair Compound Library | Anti-Pancreatic Cancer Compound Library | Histone Modification Compound Library | Bioactive Compound Library

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途