化合物SGC-CBP30 T6668

Product Introduction
Bioactivity


英文名: SGC-CBP30

描述: SGC-CBP30 是高选择性CBP/p300溴结构域的有效抑制剂，对CBP 和p300的Kd 值分别为 21 和 32 nM。它强烈减少 Th17 细胞中 IL-17A 的分泌，具有抗炎作用。

体内活性: SGC-CBP30在U2OS细胞和HeLa细胞中具有中度细胞毒性。

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: H2O : < 1 mg/mL (insoluble or slightly soluble)
Ethanol : 93 mg/mL (182.7 mM)
DMSO : 93 mg/mL (182.7 mM)


关键字: inhibit | IL-17A | HAT | HATs | BRD | Histone Acetyltransferase | ankylosing | SGCCBP30 | cells | epigenetic | spondylitis | anti-inflammatory | arthritis | SGC-CBP30 | Epigenetic Reader Domain | SGC-CBP-30 | Th17 | psoriatic | SGC CBP30 | Inhibitor

相关产品: I-CBP112 hydrochloride | Tz-Thalidomide | Piflufolastat | TPOP146 | (S,R)-CFT8634 | JQAD1 | Y06036 | LP99 | BRM/BRG1 ATP Inhibitor-1 | BRD7-IN-1

相关库: Anti-Hypertension Compound Library | Bioactive Compounds Library Max | Inhibitor Library | Epigenetics Compound Library | Highly Selective Inhibitor Library | Reprogramming Compound Library | Histone Modification Compound Library | NO PAINS Compound Library | Chromatin Modification Compound Library | Bioactive Compound Library

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途