盐酸替莫普利 T6698

Product Introduction
Bioactivity


英文名: Temocapril hydrochloride

描述: Temocapril hydrochloride (CS-622 HCl) 是血管紧张素转化酶 (ACE) 抑制剂。Temocapril HCl 能够用于充血性心力衰竭、急性心肌梗死、高血压、胰岛素抵抗和肾脏疾病的研究。

激酶实验: C2C12 cells are seeded into 96-well plates at 2,000 cells per well in DMEM supplemented with 2% FBS. The wells are treated in quadruplicate with BMP ligands and LDN-193189 or vehicle. The cells are collected after 6 d in culture in 50 μL Tris-buffered saline and 1% Triton X-100. The lysates are added to p-nitro-phenylphosphate reagent in 96-well plates for 1 h and then evaluated alkaline phosphatase activity (absorbance at 405 nm). Cell viability are measured and quantity by Cell Titer Aqueous One (absorbance at 490 nm), using replicate wells treated identically to those used for alkaline phosphatase measurements[1].

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: H2O : < 1 mg/mL (insoluble or slightly soluble)
Ethanol : 95 mg/mL (185.2 mM)
DMSO : 95 mg/mL (185.2 mM)


关键字: hypertension | CES1 | acute myocardial infarction | Temocapril | Angiotensin-converting Enzyme (ACE) | heart failure | Temocapril hydrochloride | insulin resistance | Inhibitor | neonatal rat cardiomyocytes | enzyme | Cu/ZnSOD | redox proteins TRX | human carboxylesterase | Angiotensin (I) | CS 622 | Temocaprilat | inhibit | angiotensin-converting | CS622 | renal diseases | Temocapril Hydrochloride | N-acetyltetradecapeptide renin substrate | Mn-SOD

相关产品: Phosphoramidon Disodium | Angiotensin 1/2 (5-7) acetate | [Sar1, Ile8]-Angiotensin II acetate | Ramipril | Methyl candesartan | Azilsartan Methyl Ester | Angiotensin (1-7) | Angiotensin II 5-valine TFA | Sacubitril/Valsartan | L-162,313

相关库: Drug Repurposing Compound Library | Approved Drug Library | Angiogenesis related Compound Library | Membrane Protein-targeted Compound Library | Anti-Metabolism Disease Compound Library | Inhibitor Library | Endocrinology-Hormone Compound Library | Target-Focused Phenotypic Screening Library | NO PAINS Compound Library | Anti-Cardiovascular Disease Compound Library

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途