杀草强 T67498

Product Introduction
Bioactivity


英文名: 3-Amino-1,2,4-triazole

描述: 3-Amino-1,2,4-triazole (Trapidil impurity B) 是一种过氧化氢酶抑制剂，能够诱导过氧化氢解毒的补偿机制。 该机制涉及增加谷胱甘肽过氧化物酶和谷胱甘肽还原酶的活性。

体外活性: Amitrole (1,10 and 100 microg/ml ) had no significant cytotoxicity to the FRTL-5 cells (P > 0.05). The concentration of thyroglobulin (TG) in the culture was decreased by 10 and 100 microg/ml amitrole (P < 0.05), and the concentration of TG in the cells was decreased by 100 microg/ml (P < 0.05) but the TTF-1 in the cells were not obviously changed (P > 0.05). The TSHR in the surface of FRTL-5 cells was significantly decreased by all doses of amitrole (P < 0.01). The influence of amitrole on TG of FRTL-5 cells may be related to significantly reduce TSHR in the surface of FRTL-5 cells.[1]

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 90.0 mg/mL (1070.4 mM)


关键字: 3-Amino-1,2,4-triazole

相关产品: L-Ascorbic acid 2-phosphate trisodium | Sodium Thiocyanate | 2-Aminoethanethiol | Psoralidin | Anticancer agent 154 | Hesperidin | Tetrahydroxyquinone | Sinapinic Acid | Emeramide | (20S)-Protopanaxadiol

相关库: Anti-Cancer Compound Library | Bioactive Compounds Library Max | Inhibitor Library | Bioactive Compound Library

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