化合物LKM38 T67835
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
5 mg | 2103360-95-6 | ¥13,300.00 | 询底价 |
50 mg | 2103360-95-6 | ¥27,300.00 | 询底价 |
1 mg | 2103360-95-6 | ¥6,130.00 | 询底价 |
25 mg | 2103360-95-6 | ¥20,500.00 | 询底价 |
Product Introduction
Bioactivity
英文名: LKM38
描述: LKM38是一种新型的重氮烷基胆固醇探针,是一种有前途的胆固醇模拟物。LKM38既能维持抗胆固醇细胞的生长,又能适当地调节关键的胆固醇平衡途径。LKM38可以作为研究胆固醇蛋白相互作用和贩运的有力工具。
体外活性: LKM38 emerged as a promising cholesterol mimic because it both sustained the growth of cholesterol-auxotrophic cells and appropriately regulated key cholesterol homeostatic pathways. When presented as an ester in lipoprotein particles, LKM38 initially localized to the lysosome and subsequently trafficked to the plasma membrane and endoplasmic reticulum. LKM38 bound to diverse, established cholesterol binding proteins. Through a detailed characterization of the cellular behavior of a panel of diazirine alkyne probes using cell biological, biochemical trafficking assays and immunofluorescence approaches, we conclude that LKM38 can serve as a powerful tool for the study of cholesterol protein interactions and trafficking.[1]
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
关键字: LKM-38 | LKM 38 | LKM38
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途