司更色林 T68141

Product Introduction
Bioactivity


英文名: Seganserin

描述: Seganserin 是一种非选择性5-羟色胺2-HT 受体拮抗剂，可逆转了氟西汀和喹帕嗪对黄体酮诱导的食欲亢进，抑郁和痛觉的抑制作用，逆转氟西汀和喹帕嗪诱导的抗抑郁和镇痛作用。

体内活性: Seganserin (2 mg/kg, i.p.; mice), a 5-HT(2) receptor antagonist pretreatment significantly reversed fluoxetine and quipazine-induced antidepressant and analgesic effects.[2] Seganserin (2 mg/kg, i.p.; mice), significantly reversed the suppressive effect of fluoxetine and quipazine on progesterone-induced hyperphagia, depression, and algesia in the hot-plate test.[2]

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 55 mg/mL (116.64 mM)


相关产品: JPC0323 | Clomipramine | Ketanserin | E6801 | Amisulpride | Azaphen | Tandospirone | (S)-Mirtazapine | JNJ-18038683 | Tiaspirone hydrochloride

相关库: Neurotransmitter Receptor Compound Library | Membrane Protein-targeted Compound Library | Bioactive Compounds Library Max | Neuronal Signaling Compound Library | GPCR Compound Library | Bioactive Compound Library

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途