化合物 Macimorelin Acetate T68276

Product Introduction
Bioactivity


英文名: Macimorelin acetate

描述: Macimorelin (EP-1572) acetate，一种 GH 促分泌素，是一种具有口服活性的GHSR 激动剂。Macimorelin acetate 可刺激 GH 的释放。Macimorelin acetate 可用于成人生长激素缺乏症 (AGHD) 和癌症厌食-恶病质综合征 (CACS) 的研究。

体外活性: NFATc1-IN-1 (0、0.5、1.0、1.5、2.0、2.5 μM, 4 days) exhibits potent inhibitory activities on osteoclast formation and function, which eventually translates into decreased bone resorption while showing no cytotoxic effects towards osteoclast precursor cells at concentrations of as high as 2.5 μM.[1] NFATc1-IN-1 (1.5-2.5 μM, 24 h) blocks NFATc1 nuclear translocation and decreases the level of NFATc1.[1]

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

关键字: D-87575 acetate | Macimorelin | EP-1572 Acetate | EP-1572 | EP-1572 acetate ; AEZS 130 Acetate | EP-1572 acetate ; AEZS-130 Acetate | EP 1572 | Macrilen | JMV 1843 | UMV-1843 | AEZS130 Acetate | EP 1572 Acetate | AEZS 130 | EP1572 | AibDTrpDgTrpCHO. Macimorelin Acetate | UMV1843 | Macimorelin Acetate | AEZS130 | AEZS-130 Acetate | UMV 1843 | JMV1843 | ARD07 | EP1572 Acetate | AEZS-130 | ARD-07 | EP-1572 acetate ; AEZS130 Acetate | JMV-1843 | AEZS 130 Acetate

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途