橄榄苦苷 T6917
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
500 mg | 32619-42-4 | ¥3,330.00 | 询底价 |
100 mg | 32619-42-4 | ¥1,330.00 | 询底价 |
5 mg | 32619-42-4 | ¥218.00 | 询底价 |
25 mg | 32619-42-4 | ¥493.00 | 询底价 |
50 mg | 32619-42-4 | ¥828.00 | 询底价 |
1 mL | 32619-42-4 | ¥298.00 | 询底价 |
10 mg | 32619-42-4 | ¥297.00 | 询底价 |
Product Introduction
Bioactivity
英文名: Oleuropein
描述: Oleuropein 在橄榄叶和油中发现的天然产物,通过 p53 依赖性途径以及 Bax 和 Bcl2基因的调控来诱导乳腺癌细胞凋亡,还抑制芳香化酶。它可通过直接抑制 PPARγ转录活性来发挥抗氧化,抗炎和抗动脉粥样硬化作用。
体外活性: In both J774A.1 cells and primary mouse macrophages, Oleuropein increases LPS-induced NO production. [1] Oleuropein prevents oxidative myocardial injury induced by ischemia and reperfusion. [2] In TF-1a; 786-O, T-47D, RPMI-7951, LoVo, and NL-Fib cells, Oleuropein inhibits cell proliferation and migration. [3]
体内活性: In swiss albino mice that spontaneously develop soft tissue sarcomas, Oleuropein (i.p. or p.o.) completely regresses tumors. [3] In rats, Oleuropein (40 mg/kg, p.o.) protects from cardiac remodeling process after isoproterenol-induced myocardial infarction through inhibiting angiotensin-converting enzyme activity. [4]
存储条件: store at low temperaturePowder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO : 50 mg/mL (92.51 mM)
H2O : 92 mg/mL (170.2 mM)
Ethanol : 93 mg/mL (172.1 mM)
关键字: PPARγ | olive | PPAR | Peroxisome proliferator-activated receptors | inhibit | Apoptosis | leaves | Aromatase | oil | Oleuropein | anti-atherogenic | cancer | antioxidant | breast | Inhibitor | anti-inflammatory
相关产品: Bigelovin | Nimustine Hydrochloride | HYPOCRELLIN B | 5'-Amino-5'-deoxyadenosine | 9-Methoxycamptothecin | L-Ascorbic acid sodium salt | ZLDI-8 | (-)-Anonaine | Melatonin | CDKI-73
相关库: Anti-Aging Compound Library | HIF-1 Signaling Pathway Compound Library | Anti-Breast Cancer Compound Library | Oxidation-Reduction Compound Library | Anti-Diabetic Compound Library | Anti-Cancer Active Compound Library | Traditional Chinese Medicine Monomer Library | Natural Product Library for HTS | Cuproptosis Compound Library | Natural Product Library
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途