磷酸特地唑胺 T6998

Product Introduction
Bioactivity


英文名: Tedizolid Phosphate

描述: Tedizolid Phosphate (TR-701FA) 是 MAO-A 和 MAO-B 抑制剂，具有抗革兰氏阳性菌的活性。

体外活性: Tedizolid (TR-700, formerly torezolid) is the active moiety of the prodrug tedizolid phosphate (TR-701), a next-generation oxazolidinone, with high potency against Gram-positive species, including methicillin-resistant Staphylococcus aureus (MRSA)[2]. Tedizolid is 4-fold more potent than linezolid against PRSP isolates in vitro[1].

体内活性: Tedizolid has excellent penetration into pulmonary epithelial lining fluid (ELF). Tedizolid phosphate administered to mice orally or intravenously is effective in vivo against systemic infection with PRSP isolates. Oral tedizolid phosphate is also effective in vivo against pneumonia induced with a PSSP strain[1].

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: H2O : < 1 mg/mL (insoluble or slightly soluble)
DMSO : 21 mg/mL (46.6 mM)
Ethanol : < 1 mg/mL (insoluble or slightly soluble)


关键字: Antibiotic | inhibit | Tedizolid | Tedizolid Phosphate | Torezolid Phosphate | Bacterial | Inhibitor

相关产品: TP-2857 | Kasugamycin hydrochloride hydrate | 4-Acetamidobutanoic acid | Acetylalkannin | p-Anisic acid | Mitonafide | Oenothein B | Thiolutin | Quinupristin | Sulfabenzamide

相关库: FDA-Approved Drug Library | Drug Repurposing Compound Library | Approved Drug Library | Antibiotics Library | Inhibitor Library | EMA Approved Drug Library | Anti-Bacterial Compound Library | Orally Active Compound Library | NO PAINS Compound Library | Bioactive Compound Library

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途