化合物VPS34-IN1 T7015
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
100 mg | 1383716-33-3 | ¥5,160.00 | 询底价 |
50 mg | 1383716-33-3 | ¥3,570.00 | 询底价 |
5 mg | 1383716-33-3 | ¥822.00 | 询底价 |
10 mg | 1383716-33-3 | ¥1,390.00 | 询底价 |
1 mL | 1383716-33-3 | ¥861.00 | 询底价 |
25 mg | 1383716-33-3 | ¥2,390.00 | 询底价 |
1 mg | 1383716-33-3 | ¥335.00 | 询底价 |
2 mg | 1383716-33-3 | ¥477.00 | 询底价 |
Product Introduction
Bioactivity
英文名: Vps34-IN-1
描述: Vps34-IN-1 (VPS34-IN1) 是一种有效且高度选择性的 Vps34 抑制剂,可调节自噬,IC50为4nM。
体外活性: Administration of VPS34-IN1 to cells induces a rapid dose-dependent dispersal of a specific PtdIns(3)P-binding probe from endosome membranes, within 1min, without affecting the ability of class I PI3K to regulate Akt. It can also induce a rapid ~50-60% loss of SGK3 phosphorylation within 1min. VPS34-IN1 has no inhibition to the SGK2 isoform that does not possess a PtdIns(3)P-binding PX domain[1].
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: H2O : < 1 mg/mL (insoluble or slightly soluble)
Ethanol : 79 mg/mL (185.5 mM)
DMSO : 79 mg/mL (185.5 mM)
关键字: inhibit | Autophagy | Vps34IN1 | PI3K | Vps-34-IN-1 | Inhibitor | Phosphoinositide 3-kinase | Vps34-IN-1 | Vps34 IN 1
相关产品: 740 Y-P(TFA)(1236188-16-1 free base) | MOMIPP | CXJ-2 | Umbralisib | NIBR-17 | YH-306 | PI3K-IN-10 | 3-Methyladenine | 8-Prenylkaempferol | ZSTK474
相关库: Antioxidant Compound Library | Anti-Prostate Cancer Compound Library | Anti-Liver Cancer Compound Library | Bioactive Compounds Library Max | Inhibitor Library | Kinase Inhibitor Library | Anti-Obesity Compound Library | Highly Selective Inhibitor Library | Anti-Pancreatic Cancer Compound Library | Covalent Inhibitor Library
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途