7-甲氧基香豆素 T7049

Product Introduction
Bioactivity


英文名: Herniarin

描述: Herniarin (Ayapanin) 是一种常见的天然香豆素类化合物，存在于开花植物，具有抗肿瘤的活性。

体外活性: Herniarin is cytotoxic to breast carcinoma cell line MCF-7 (IC50: 207.6 μM). Herniarin (100 μM) also induces apoptosis in MCF-7 cells [1]. Herniarin alone has no obvious cytotoxicity on transitional cell carcinoma (TCC) cells, but when in combination with 5?μg/mL cisplatin, Herniarin (80 μg/mL) potently enhances the antitumor effect of cisplatin and increases chromatin condensation [2].

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 50 mg/mL (283.82 mM)


关键字: Inhibitor | inhibit | Herniarin

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