对羟基肉桂酸 T7053

Product Introduction
Bioactivity


英文名: p-Hydroxycinnamic acid

描述: p-Hydroxycinnamic acid (NSC-59260) 是常见的食用酚，可抑制血小板活性，对血栓素 B2 和前列腺素 E2 的 IC50值分别为 371 和 126 μM。

体外活性: p-Hydroxycinnamic acid (500 μM and 1 mM) reduces ADP-induced platelet aggregation (55?2 (SE 4?01) % and 35?6 (SE 2?35) % relative to the basal level, respectively). p-Hydroxycinnamic acid is able to modify platelet function, a shear-inducing device that simulates primary hemostasis. p-Hydroxycinnamic acid interferes also with arachidonic acid cascade, reducing thromboxane B2 production and lipopolysaccharide-induced prostaglandin E2 generation (IC50 371 and 126 μM, respectively)[1].

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 6.25 mg/mL (38.07 mM)


关键字: Inhibitor | Prostaglandin Receptor | p Hydroxycinnamic acid | NSC-59260 | p-Hydroxycinnamic acid | NSC59260 | pHydroxycinnamic acid | inhibit | Endogenous Metabolite

相关产品: Enoxaparin sodium | Imitrodast | Odiparcil | TFLLRNPNDK-NH2 | Menadione | Ximelagatran | Melagatran | Efegatran sulfate | Naroparcil | Dabigatran ethyl ester

相关库: Tobacco Monomer Library | Selected Plant-Sourced Compound Library | Membrane Protein-targeted Compound Library | Inhibitor Library | GPCR Compound Library | Traditional Chinese Medicine Monomer Library | Miao medicine Compound Library | Tibetan medicine Compound Library | Protease Inhibitor Library | Mouse Metabolite Compound Library

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途