化合物 Azalanstat HCl T70660
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
25 mg | 143484-82-6 | ¥10,600.00 | 询底价 |
50 mg | 143484-82-6 | ¥13,800.00 | 询底价 |
100 mg | 143484-82-6 | ¥17,500.00 | 询底价 |
Product Introduction
Bioactivity
英文名: Azalanstat HCl
描述: Azalanstat HCl is an anti-obesity drug acting as a lanosterol 14α-demethylase inhibitor. Azalanstat HCl has been shown to inhibit cholesterol synthesis in HepG2 cells, human fibroblasts, hamster hepatocytes and hamster liver, by inhibiting the cytochrome P450 enzyme lanosterol 14 alpha-demethylase. When administered orally to hamsters fed regular chow, RS-21607 (50 mg/kg/day) lowered serum cholesterol in a dose-dependent manner (ED50 = 62 mg/kg) in a period of 1 week. It preferentially lowered low density lipoprotein (LDL) cholesterol and apo B relative to high density lipoprotein (HDL) cholesterol and apo A-1.
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
关键字: UCSF-924NC | UCSF 924NC | ZINC000091707446 | ZINC 000091707446 | Azalanstat HCl | ZINC-000091707446
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途