化合物 3-Oxobetulin Acetate T70856
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
25 mg | 136587-07-0 | ¥9,320.00 | 询底价 |
5 mg | 136587-07-0 | ¥2,430.00 | 询底价 |
10 mg | 136587-07-0 | ¥4,250.00 | 询底价 |
1 mg | 136587-07-0 | ¥560.00 | 询底价 |
Product Introduction
Bioactivity
英文名: 3-Oxobetulin Acetate
描述: 3-Oxobetulin acetate is a derivative of the cholesterol biosynthesis inhibitor betulin. It inhibits the growth of P388 murine lymphocytic leukemia cells (EC50 = 0.12 µg/ml), as well as human MCF-7 breast, SF-268 CNS, H460 lung, and KM20L2 colon cancer cells (GI50s = 8, 10.6, 5.2, and 12.7 µg/ml, respectively), but not BxPC-3 pancreas or DU145 prostate cancer cells (GI50s = >10 µg/ml for both). 3-Oxobetulin acetate inhibits replication of X4 tropic recombinant HIV (NL4.3-Ren) in MT-2 lymphoblastoid cells (IC50 = 13.4 µM). It is also active against L. donovani amastigotes when used at a concentration of 50 µM.
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
关键字: GSK-2269557H | Nemiralisib succinate | 3-Oxobetulin Acetate | GSK 2269557H
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途