化合物 AC430 T70870

Product Introduction
Bioactivity


英文名: AC430

描述: AC430 is a potent and specific small molecule inhibitor of janus kinase 2 (JAK2), which has been implicated as a target for therapy in both oncology and autoimmune disease. AC430 is currently being developed by Ambit. In preclinical studies, AC430 has exhibited potency against JAK2 and V617F mutated JAK2 in cell-based models that is at least equivalent to, and in most cases superior to, competing JAK2 inhibitors. In preclinical oncology and autoimmune models, AC430 is well tolerated and has significant efficacy at oral doses as low as 10 mg/kg/day.

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

关键字: AC430 | Smurf1-inhibitor-1 | Smurf1inhibitor1 | AC-430 | AC 430

化合物 AC430 T70870信息由TargetMol中国为您提供，如您想了解更多关于化合物 AC430 T70870报价、型号、参数等信息，欢迎来电或留言咨询。

注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途