化合物 DC-120 T71097
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
100 mg | 1261080-40-3 | ¥25,500.00 | 询底价 |
25 mg | 1261080-40-3 | ¥15,000.00 | 询底价 |
50 mg | 1261080-40-3 | ¥19,800.00 | 询底价 |
Product Introduction
Bioactivity
英文名: DC-120
描述: DC-120 is an ATP competitive AKT kinase inhibitor that suppressed proliferation and induced apoptosis in liver cancer cells both in vitro and in vivo. DC120 blocked the phosphorylation of downstream molecules in the AKT signal pathway in dose- and time-dependent manners both in vitro and in vivo. DC120 inhibits AKT activity in vitro with an EC(50) of 153 nM. DC120 at 20 mg/kg/day inhibited the CNE2 xenograft tumor growth with a treated group/control group ratio of 38.1%, accompanied by increasing terminal deoxynucleotidyl transferasedUTP nick-end labeling-positive cells in the tumor sample.
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
关键字: DC120 | LLL 12 | LLL-12 | DC 120 | DC-120
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途