400-6699-1171000

分析测试百科网 认证会员,请放心拨打!

首页> 产品展示> 化合物 MPT0B214 T71217
普通会员

诚信认证:

工商注册信息已核实!

快速导航
品牌
其他生物化学试剂

化合物 MPT0B214 T71217

英文名称:MPT0B214
品牌 厂商性质 产地 货期
TargetMol 生产商 美国 现货

性能特点

生化试剂,可用于动物细胞实验

在线咨询 询底价
AI问答
配套的仪器设备? 可以搭配的相关耗材试剂?
产品参数
规格 CAS号 价格 操作
50 mg 1215208-65-3 ¥13,800.00 询底价
100 mg 1215208-65-3 ¥17,500.00 询底价
25 mg 1215208-65-3 ¥10,600.00 询底价
产品介绍

Product Introduction
Bioactivity


英文名: MPT0B214

描述: MPT0B214 is a novel and potent microtubule inhibitor with potential anticancer activity. MPT0B214 inhibited tubulin polymerization through strongly binding to the tubulin's colchicine-binding site and had cytotoxic activity in a variety of human tumor cell lines. After treatment with MPT0B214, KB cells were arrested in the G2-M phase before cell death occurred, which were associated with upregulation of cyclin B1, dephosphorylation of Cdc2, phosphorylation of Cdc25C and elevated expression of the mitotic marker MPM-2. Furthermore, the compound induced apoptotic cell death through mitochondria/caspase 9-dependent pathway. Notably, several KB-derived multidrug-resistant cancer cell lines were also sensitive to MPT0B214 treatment. ( PLoS One. 2013;8(3):e58953).

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

关键字: MPT0B-214 | S11566 | MPT0B 214 | MPT0B214 | S-11566

化合物 MPT0B214 T71217信息由TargetMol中国为您提供,如您想了解更多关于化合物 MPT0B214 T71217报价、型号、参数等信息,欢迎来电或留言咨询。

注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途

店铺推荐
  • 品牌:TargetMol
    蛋白酶抑制剂 Cocktail (EDTA-Free, 100× in DMSO) C0001

    蛋白酶抑制剂 Cocktail (EDTA-Free, 100× in DMSO) C0001

    询价
  • 品牌:TargetMol
    磷酸酶抑制剂 Cocktail I (100× ddH2O) C0002

    磷酸酶抑制剂 Cocktail I (100× ddH2O) C0002

    询价
  • 品牌:TargetMol
    磷酸酶抑制剂 Cocktail II (100× DMSO) C0003

    磷酸酶抑制剂 Cocktail II (100× DMSO) C0003

    询价
  • 品牌:TargetMol
    磷酸酶抑制剂 Cocktail III (2 Tubes, 100x) C0004

    磷酸酶抑制剂 Cocktail III (2 Tubes, 100x) C0004

    询价
  • 品牌:TargetMol
    Cell Counting Kit-8 (CCK-8) C0005

    Cell Counting Kit-8 (CCK-8) C0005

    询价
  • 品牌:TargetMol
    SYBR Green qPCR Master Mix (No ROX) C0006

    SYBR Green qPCR Master Mix (No ROX) C0006

    询价