化合物 Opaganib HCl T71301
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
100 mg | 1185157-59-8 | ¥17,500.00 | 询底价 |
50 mg | 1185157-59-8 | ¥13,800.00 | 询底价 |
25 mg | 1185157-59-8 | ¥10,600.00 | 询底价 |
Product Introduction
Bioactivity
英文名: Opaganib HCl
描述: ABC294640, also known as Opaganib, is an orally available, aryladamantane compound and selective inhibitor of sphingosine kinase-2 (SK2) with potential antineoplastic activity. Upon administration, ABC294640 competitively binds to and inhibits SK2, thereby preventing the phosphorylation of the pro-apoptotic amino alcohol sphingosine to sphingosine 1-phosphate (S1P), the lipid mediator that is pro-survival and critical for immunomodulation. This may eventually lead to the induction of apoptosis and may result in an inhibition of cell proliferation in cancer cells overexpressing SK2.
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
关键字: Fluphenamic Acid d4 | Opaganib HCl | Fluphenamic Acid-d4 | FFA d4 | FFA-d4 | Flufenamic Acid d4
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途