化合物360A T7409
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
1 mg | 794458-56-3 | ¥935.00 | 询底价 |
100 mg | 794458-56-3 | ¥9,870.00 | 询底价 |
2 mg | 794458-56-3 | ¥1,490.00 | 询底价 |
50 mg | 794458-56-3 | ¥7,520.00 | 询底价 |
5 mg | 794458-56-3 | ¥2,130.00 | 询底价 |
10 mg | 794458-56-3 | ¥3,260.00 | 询底价 |
25 mg | 794458-56-3 | ¥5,330.00 | 询底价 |
Product Introduction
Bioactivity
英文名: 360A
描述: 360A 是一种稳定的G-四链体配体,还抑制 TRAP-G4 试验中端粒酶的端粒酶活性,IC50值为 300 nM。
细胞实验: Supplemented with 10% fetal calf serum (FCS) and 1% penicillin/streptomycin. A549 cells were maintained in humidified incubators at 37 °C in an atmosphere containing 5% CO2 and ambient oxygen of 20%. Cells were grown in 25 cm^2 flasks (150,000 cells/flask) and treated with 5 μM of 360A or (360A)2A every 3 or 4 days (i.e., at each reseeding) until cultures were terminated. Control cells were either non-treated or treated with 0.1% DMSO. At each reseeding the remaining cells were pelleted and snap frozen for further DNA extraction.Statistical analysis was performed using GraphPad Prism 5. A Chi-square test was used to compare TDEs frequencies[1].
体外活性: 向A549肺癌细胞系处理5 μM 360A,可以在11天的治疗内抑制细胞增殖。使用新合成的二聚体(360A)2A处理,产生了相当的抗增殖效果[1]。
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO : Slightly soluble
关键字: 360A | Telomerase | inhibit | Inhibitor | G-quadruplex
相关产品: ART812 | Apricitabine | 6-Thio-2'-Deoxyguanosine | Zoliflodacin | Poly(A) polymerase | Enrofloxacin | Halofuginone hydrobromide | NSC 617145 | HAMNO | Trovafloxacin mesylate
相关库: Anti-Aging Compound Library | Cell Cycle Compound Library | Anti-Cancer Compound Library | Bioactive Compounds Library Max | Inhibitor Library | DNA Damage & Repair Compound Library | Target-Focused Phenotypic Screening Library | Bioactive Compound Library
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途