2，2-双（4-氯苯基）-1，1-二氯乙烯 T7440

Product Introduction
Bioactivity


英文名: p,p'-DDE

描述: p,p'-DDE (p,p'-dichlorodiphenyldichloroethylene) 是持久性 DDT 的主要代谢物。4,4'-DDE 是一种有效的雄激素受体拮抗剂，IC50=5 μM，Ki=3.5 μM。

体外活性: 4,4'-DDE inhibits estrogen binding to rainbow trout estrogen receptors (rtERs) with an IC50 value of 8 μM[1]

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 63mg/mL(198.09mM)


关键字: Inhibitor | effectsin | Androgen Receptor | developmental | p,p'-DDE | vivoand | inhibit | metabolite | antiandrogenic | transcriptional | Drug Metabolite | p,p' DDE | p,p'DDE

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