阿德福韦 T7447
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
10 mg | 106941-25-7 | ¥272.00 | 询底价 |
100 mg | 106941-25-7 | ¥980.00 | 询底价 |
25 mg | 106941-25-7 | ¥417.00 | 询底价 |
50 mg | 106941-25-7 | ¥671.00 | 询底价 |
Product Introduction
Bioactivity
英文名: Adefovir
描述: Adefovir 是一种单磷酸腺苷类似物抗病毒剂,在细胞内转化为 Adefovir diphosphate 后可抑制HBVDNA 聚合酶。它在 HepG2.2.15 细胞系中对HBV 的IC50为 0.7 μM。它对多种病毒(包括HBV 和疱疹病毒)具有良好的抗病毒活性。
细胞实验: The effect of adefovir on viral CCC DNA synthesis was examined with primary cultures of DHBV-infected fetal hepatocytes.?Adefovir was administered for six consecutive days starting one day before or four days after DHBV inoculation.?Dose-dependent inhibition of both virion release in culture supernatants and synthesis of intracellular viral DNA was observed[1].
体外活性: adefovir is a potent inhibitor of DHBV replication that inhibits CCC DNA amplification but does not effectively prevent the formation of CCC DNA from incoming viral genomes[1].
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: H2O : 2.5 mM
DMSO : Insoluble
关键字: HBV | PMEA | Adefovir | diphosphate | monophosphate | GS-0393 | herpesviruses | antiviral | adenosine | GS 0393 | transcriptase | Hepatitis B virus | Inhibitor | reverse | HIV | GS0393 | Reverse Transcriptase | inhibit
相关产品: Paederoside | OSS_128167 | Niranthin | Sophoranol | Oleana-2,12-dien-28-oic acid | Periglaucine A | Adefovir dipivoxil | Pradefovir | Periglaucine B | HBV-IN-35
相关库: Drug Repurposing Compound Library | Anti-COVID-19 Compound Library | ReFRAME Related Library | Anti-Cancer Drug Library | Clinical Compound Library | Inhibitor Library | Anti-Cancer Clinical Compound Library | Orally Active Compound Library | NO PAINS Compound Library | Anti-Viral Compound Library
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途