O-6-苄基鸟嘌呤 T7539

Product Introduction
Bioactivity


英文名: O6-Benzylguanine

描述: O6-Benzylguanine 是鸟嘌呤类似物，是 DNA 修复酶 O6 烷基鸟嘌呤DNA 烷基转移酶(MGMT/AGT)抑制剂，可诱导肿瘤细胞凋亡，具有抗肿瘤活性。它作为 AGT 底物，将其苄基转移到 AGT 半胱氨酸残基上，从而不可逆地灭活 AGT 并阻止 DNA 修复。

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 48mg/mL(198.96mM)


关键字: pancreatic | DNA/RNA Synthesis | transcriptional | PARP1 | p53 | inhibit | cyclin | O-6-Benzylguanine | antineoplastic | cancer | O6Benzylguanine | O6 Benzylguanine | guanine | Inhibitor | p21 | analog | Apoptosis | O6-Benzylguanine

相关产品: PD168393 | Anticancer agent 43 | 14-Deoxyandrographolide | Nobiletin | Tubulin inhibitor 35 | Meclizine dihydrochloride | rac-CCT-250863 HCl | Ritonavir | Samuraciclib hydrochloride | D609

相关库: Drug Repurposing Compound Library | Anti-Liver Cancer Compound Library | Anti-Cancer Drug Library | Clinical Compound Library | Human Metabolite Library | Anti-Cancer Clinical Compound Library | Inhibitor Library | Tyrosine Kinase Inhibitor Library | Anti-Cancer Active Compound Library | NO PAINS Compound Library

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途