碘塞罗宁 T7578

Product Introduction
Bioactivity


英文名: REVERSE T3

描述: Reverse T3 (3,3',5'-triiodo-L-thyronine) 是由甲状腺素原脱碘后产生的甲状腺激素。它可抑制由其它甲状腺激素类似物引起的新生大鼠心肌细胞中钠电流增加的作用。

细胞实验: Brain death (BD) was induced in mechanically ventilated rats by inflation of a Fogarty catheter in the epidural space.?T3 (0.1 mg/kg) or vehicle was administered intraperitoneally 2 h prior to BD induction.?After 4 h of BD, serum and liver tissue were collected.?RT-qPCR, routine biochemistry, and immunohistochemistry were performed[1].

体外活性: Reverse T3(T3) pre-conditioning leads to beneficial effects in the liver of brain-dead rats as seen by lower cellular injury and reduced apoptosis, and supports the suggested role of reverse T3(T3) hormone therapy in the management of brain-dead donors[1].

存储条件: store at low temperaturePowder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 32.55mg/mL(50mM)


关键字: Reverse T 3 | THR | REVERSE T-3 | REVERSE T3 | Thyroid Hormone Receptor | inhibit | Inhibitor | 3′,5′,3-Triiodothyronine

相关产品: Liothyronine | Sobetirome | Eprotirome | Carbimazole | Propylthiouracil | DPC AJ1951 acetate | Glutaurine aceate | Tiratricol | CO23 | 3,5-Diiodothyropropionic acid

相关库: Bioactive Compounds Library Max | Inhibitor Library | Nuclear Receptor Compound Library | Endocrinology-Hormone Compound Library | NO PAINS Compound Library | Bioactive Compound Library

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途