化合物Substance P (1-7) 2TFA T7675

Product Introduction
Bioactivity


英文名: Substance P (1-7) 2TFA(68060-49-1(free base))

描述: Substance P (1-7) 2TFA(68060-49-1(free base)) 是速激肽P（SP）蛋白水解降解后形成的主要生物活性代谢物，具有抗炎、抗伤害和抗痛觉过敏作用。

体内活性: Substance P 1-7, SP(1-7), which is the main SP fragment in rat CNS, was injected intranigrally. SP(1-7) was found to act as a very potent antagonist against the SP-induced responses and was formed locally in the nigra after SP injection. It is proposed that SP(1-7) is an endogenous modulator of SP actions. Generation of peptide fragments, which retain receptor affinity but not efficacy, may be a general mechanism for autoregulation in peptidergic systems[1].

存储条件: keep away from moisturePowder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 10 mM


关键字: Substance P (1 7) 2TFA(68060 49 1(free base)) | Substance P (17) 2TFA(68060491(free base)) | Substance P 2TFA(68060-49-1(free base))

相关库: Bioactive Compounds Library Max | Peptide Compound Library | NO PAINS Compound Library | Bioactive Compound Library

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途