丙酮酸钠 T7717

Product Introduction
Bioactivity


英文名: Sodium 2-oxopropanoate

描述: Sodium 2-oxopropanoate (Sodium pyruvate) 是 pyruvate 的钠盐形式。pyruvate 是葡萄糖的三碳代谢物，是一种在糖酵解途径中产生的化合物，它是一种能够清除 ROS 的自由基清除剂。

动物实验: In the pollen season, all the participants were given corticosteroid nasal spray of standard dose for two weeks, and during the next two weeks they were randomized to treatment group (n = 23) taking nasal sodium pyruvate, and control group (n = 30) without sodium pyruvate.?Daily rhinoconjunctivitis symptom score and daily rescue medication score were analyzed.?Also the fraction of exhaled nitric oxide of the upper airway was measured before and after the treatment of sodium pyruvate[1].

体内活性: Sodium pyruvate nasal spray was effective in attenuating the rhinoconjunctivitis symptoms and reducing the rescue medication use of allergic rhinitis patients[1].

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 1.1 mg/mL (10 mM)


关键字: Reactive Oxygen Species | Endogenous Metabolite | Sodium 2-oxopropanoate | Inhibitor | Sodium Pyruvate | radical | free | Sodium 2oxopropanoate | inhibit | ROS | scavenger | Sodium 2 oxopropanoate | Glycolysis | Glucose

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途