分散橙1 T7857

Product Introduction
Bioactivity


英文名: DO1

描述: DO1 (Disperse Orange 1) 是一种抗淀粉样蛋白剂，可在亚化学计量浓度下有效延迟种子和非种子 Aβ42 聚合。

体内活性: DO1 disrupts preformed fibrillar assemblies of synthetic Aβ42 peptides and decreases the seeding activity of Aβ aggregates from brain extracts of AD transgenic mice.?DO1 also reduced the size and abundance of diffuse Aβ plaques and decreased neuroinflammation-related gene expression changes in brains of 5xFAD transgenic mice[1].

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 3.18 mg/mL (10 mM)


关键字: DO-1 | DO 1 | DO1

相关库: Bioactive Compounds Library Max | Bioactive Compound Library

分散橙1 T7857信息由TargetMol中国为您提供，如您想了解更多关于分散橙1 T7857报价、型号、参数等信息，欢迎来电或留言咨询。

注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途