反苯环丙胺半硫酸盐 T7942
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
100 mg | 13492-01-8 | ¥415.00 | 询底价 |
Product Introduction
Bioactivity
英文名: Tranylcypromine hemisulfate
描述: Tranylcypromine hemisulfate (Tranylcypromine Sulfate) 是单胺氧化酶(MAO) 和赖氨酸特异性去甲基化酶 1 (LSD1) 的抑制剂,可用于研究抑郁症和子宫内膜异位症。
动物实验: The authors evaluated whether tranylcypromine contributes to neuronal survival following stress-induced damage using primary cultured rat RGCs and in vivo N-methyl-D-aspartate (NMDA)-induced excitotoxicity.?Additionally, the molecules associated with tranylcypromine treatment were assessed by microarray and immunoblot analysis[1].
体内活性: Tranylcypromine-induced transcriptional and epigenetic regulation modulated RGC survival via the promotion of p38 MAPKγ activity. Therefore, pharmacologic treatments that suppress LSD1 activity may be a novel therapeutic strategy that can be used to treat neurodegenerative diseases[1].
存储条件: store at low temperaturePowder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: H2O : 10 mg/mL (54.8 mM)
DMSO : 3.33 mg/mL (18 mM)
关键字: dl-Tranylcypromine hemisulfate | Monoamine Oxidase | Tranylcypromine | Tranylcypromine Hemisulfate | Tranylcypromine hemisulfate | Histone Demethylase | inhibit | Inhibitor | MAO
相关产品: NCGC00244536 | GSK-J1 | LSD1-IN-5 | Methylstat | T-3775440 hydrochloride | CPI-455 HCl | GSK467 | IOX1 | JMJD7-IN-1 | T-448 free base
相关库: FDA-Approved Drug Library | Drug Repurposing Compound Library | Anti-Neurodegenerative Disease Compound Library | Inhibitor Library | Epigenetics Compound Library | Methylation Compound Library | Covalent Inhibitor Library | NO PAINS Compound Library | Chromatin Modification Compound Library | Bioactive Compound Library
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