化合物BMS-1001 T8470
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
1 mg | 2113650-03-4 | ¥882.00 | 询底价 |
100 mg | 2113650-03-4 | ¥10,900.00 | 询底价 |
10 mg | 2113650-03-4 | ¥3,590.00 | 询底价 |
50 mg | 2113650-03-4 | ¥7,930.00 | 询底价 |
5 mg | 2113650-03-4 | ¥2,230.00 | 询底价 |
1 mL | 2113650-03-4 | ¥2,860.00 | 询底价 |
25 mg | 2113650-03-4 | ¥5,820.00 | 询底价 |
Product Introduction
Bioactivity
英文名: BMS-1001
描述: BMS-1001 是一种有效的 PD-1/PD-L1 相互作用抑制剂(IC50:2.25 nM,在均相时间分辨荧光结合试验中)。
体外活性: The small-molecule inhibitors of the PD-1/PD-L1 interaction, BMS-1001 , ?bind to human PD-L1 and block its interaction with PD-1, when tested on isolated proteins.?The compounds present low toxicity towards tested cell lines and block the interaction of soluble PD-L1 with the cell surface-expressed PD-1.?BMS-1001 alleviate the inhibitory effect of the soluble PD-L1 on the T-cell receptor-mediated activation of T-lymphocytes.?Moreover, the compounds were effective in attenuating the inhibitory effect of the cell surface-associated PD-L1.
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO : 5.94 mg/mL (10 mM)
关键字: BMS 1001 | BMS-1001 | BMS1001
相关产品: Eciskafusp alfa | PDL-1 cpd 10 | CAY10678 | Rosnilimab | PD-1/PD-L1-IN-33 | Spartalizumab | Pidilizumab | Avelumab | LSD1-IN-27 | BMS-1166-N-piperidine-CO-N-piperazine dihydrochloride
相关库: Anti-Liver Cancer Compound Library | Anti-Breast Cancer Compound Library | Cell Cycle Compound Library | Immuno-Oncology Compound Library | Bioactive Compounds Library Max | Inhibitor Library | Apoptosis Compound Library | Target-Focused Phenotypic Screening Library | NO PAINS Compound Library | Bioactive Compound Library
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途