化合物C-170 T9028

Product Introduction
Bioactivity


英文名: STING-IN-2

描述: STING-IN-2 (C-170) 是一种 STING 共价抑制剂，可抑制小鼠 STING (mmSTING) 和人类 STING (hsSTING)，可用于自身炎症性疾病的研究。

体外活性: In THP-1 cells, pretreated with STING-IN-2 (C-170;?0.5 μM) and stimulated with cGAMP.?STING-IN-2 (C-170) treatment decreases the IFNB1 and TNF mRNA levels, and also reduces the p-TBK1 levels

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 22.5 mg/mL (78.04 mM)


关键字: Inhibitor | autoinflammatory | STING | ERIS | MPYS | cGAMP | MITA | IFNB1 | STING IN 2 | Stimulator of Interferon Genes | C 170 | TMEM173 | STING-IN-2 | C170 | inhibit | palmitoylation | STINGIN2 | p-TBK1 | TNF

相关产品: F-CRI1 | Anti-inflammatory agent 65 | STING activator Compound 53 | SAP-04 | ChX710 | Vadimezan | STING (WT/R232) activity regulator 126 | C-176 | Antitumor agent-114 | SN-001

相关库: Immuno-Oncology Compound Library | Bioactive Compounds Library Max | Inhibitor Library | NO PAINS Compound Library | Covalent Inhibitor Library | Bioactive Compound Library

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途