化合物TC11 T9083
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
2 mg | 100823-03-8 | ¥355.00 | 询底价 |
100 mg | 100823-03-8 | ¥5,360.00 | 询底价 |
10 mg | 100823-03-8 | ¥947.00 | 询底价 |
50 mg | 100823-03-8 | ¥3,730.00 | 询底价 |
25 mg | 100823-03-8 | ¥1,980.00 | 询底价 |
1 mL | 100823-03-8 | ¥749.00 | 询底价 |
5 mg | 100823-03-8 | ¥573.00 | 询底价 |
500 mg | 100823-03-8 | ¥11,200.00 | 询底价 |
1 mg | 100823-03-8 | ¥248.00 | 询底价 |
Product Introduction
Bioactivity
英文名: TC11
描述: TC11 (1H-Isoindole-1,3(2H)-dione, 5-amino-2-[2,6-bis(1-methylethyl)phenyl]-TC11) 是一种有效的肿瘤细胞增殖抑制剂,并通过激活 caspase-3、8 和 9 诱导细胞凋亡。在长时间有丝分裂阻滞期间,它诱导 MCL1降解导致凋亡。它作为苯酞酰亚胺衍生物在结构上与免疫调节药物相关。
体内活性: TC11 shows in vivo activity against multiple myeloma cell line KMS34 tumor xenografts in ICR/SCID mice. TC11 induces disruption of tubulin polymerization leading to mitotic arrest and promotes degradation of anti-apoptotic protein, MCL1, by sustained CDK1 activation.
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO : 45 mg/mL (139.57 mM)
关键字: Cyclin dependent kinase | Apoptotic | Mitotic | CLT003 | Inhibitor | Immunomodulatory | TC 11 | CLT 003 | Derivative | TC11 | inhibit | CDK | Bcl-2 Family | TC-11 | Antitumor | Phenylphthalimide | Death | Caspase
相关产品: Rasagiline | BCL6-IN-6 | (E)-Ferulic acid | 2-Methoxystypandrone | Isolimonexic acid | Serratenediol | Isochamaejasmine | Kurarinone | Gossypol | BCL6-IN-3
相关库: Anti-Neurodegenerative Disease Compound Library | Anti-Breast Cancer Compound Library | Mitochondria-Targeted Compound Library | Anti-Cancer Compound Library | Kinase Inhibitor Library | Inhibitor Library | Apoptosis Compound Library | PPI Inhibitor Library | Anti-Pancreatic Cancer Compound Library | Protease Inhibitor Library
化合物TC11 T9083信息由TargetMol中国为您提供,如您想了解更多关于化合物TC11 T9083报价、型号、参数等信息,欢迎来电或留言咨询。
注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途