化合物8-Azaadenosine T9111
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
1 mg | 10299-44-2 | ¥348.00 | 询底价 |
25 mg | 10299-44-2 | ¥2,730.00 | 询底价 |
100 mg | 10299-44-2 | ¥5,830.00 | 询底价 |
10 mg | 10299-44-2 | ¥1,230.00 | 询底价 |
50 mg | 10299-44-2 | ¥3,970.00 | 询底价 |
1 mL | 10299-44-2 | ¥898.00 | 询底价 |
5 mg | 10299-44-2 | ¥813.00 | 询底价 |
Product Introduction
Bioactivity
英文名: 8-Azaadenosine
描述: 8-Azaadenosine 是 ADAR1抑制剂和是 A-to-I 编辑抑制剂。它可阻断 RNA 编辑并抑制甲状腺癌细胞的增殖、3D 生长、侵袭和迁移。
体外活性: 8-azaadenosine (8-aza-AR) was a potent inhibitor of purine synthesis de novo, but 8-aza-HR, at concentrations much higher than the inhibitory concentration of 8-aza-AR, did not inhibit this process.?In H. Ep. 2 cells, 8-aza-HR blocked the conversion of orotic acid to uridine nucleotides and caused an accumulation of orotidine.?This inhibition of pyrimidine biosynthesis apparently does not contribute significantly to the cytotoxicity of 8-aza-HR because uridine provided no degree of reversal of its inhibition of the growth of cell cultures.
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO : 250 mg/mL (932.04 mM)
关键字: thyroid | inhibit | editing | LIN28B | invasion | proliferation | Cal62 | migration | 8Azaadenosine | RNA | ADAR1 | TPC1 | 8-Azaadenosine | Inhibitor | Adenosine Deaminase | 8 Azaadenosine
相关产品: Erdosteine | Hibifolin | Cladribine | Pentostatin | 3’-O-Methyladenosine
相关库: Anti-Cancer Compound Library | Bioactive Compounds Library Max | Inhibitor Library | Anti-Cancer Active Compound Library | Metabolism Compound Library | NO PAINS Compound Library | Bioactive Compound Library
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途