化合物 3344 T9184

Product Introduction
Bioactivity


英文名: Compound 3344

描述: Compound 3344 是 KRAS-效应器相互作用的抑制剂，亲和力为126nm。

体外活性: In vitro competition studies of 3344 binding to KRAS-G12V in waterLOGSY NMR show the anti-RAS scFv inhibits 3344 binding to KRAS. In view of the in vitro inhibition by the anti-RAS scFv of 3344 binding to RASand because the iDAb RAS interferes with BRET signal in cells, 3344 was used for valida?tion of the BRET2 toolbox for RAS-effector PPI inhibitors.

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

关键字: Compound 3344

相关产品: CCG-100602 | Antifungal agent 46 | KRAS G12C inhibitor 13 | K-Ras(G12C) inhibitor 12 | ARS-1620 | KRAS G12D inhibitor 14 | BI-2493 | RMC-7977 | EHop-016 | Kobe2602

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途