化合物JH-X-119-01 T9203
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
1 mL | 2227368-54-7 | ¥1,590.00 | 询底价 |
25 mg | 2227368-54-7 | ¥3,970.00 | 询底价 |
10 mg | 2227368-54-7 | ¥2,220.00 | 询底价 |
1 mg | 2227368-54-7 | ¥597.00 | 询底价 |
5 mg | 2227368-54-7 | ¥1,470.00 | 询底价 |
50 mg | 2227368-54-7 | ¥5,680.00 | 询底价 |
100 mg | 2227368-54-7 | ¥7,930.00 | 询底价 |
500 mg | 2227368-54-7 | ¥15,900.00 | 询底价 |
2 mg | 2227368-54-7 | ¥878.00 | 询底价 |
Product Introduction
Bioactivity
英文名: JH-X-119-01
描述: JH-X-119-01 是白介素 1 受体相关激酶 1 的选择性抑制剂。它能够改善 LPS 诱导的小鼠败血症。它可以抑制 IRAK1(IC50:9 nM),在浓度达到 10 μM 时,也不会对 IRAK4 产生抑制作用。
体外活性: JH-X-119-01 exhibited cytotoxic activity at single digit micromolar concentrations in a panel of WM, DLBCL, and lymphoma cell lines expressing MYD88.?Cotreatment of JH-X-119-01 with the BTK inhibitor ibrutinib resulted in synergistic killing effects in these systems.
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO : 12 mg/ml (26.52 mM)
关键字: JH-X-119-01 | inhibit | MYD88 | IRAK | IL-1R associated kinase | Waldenstr?m | Inhibitor | IRAK1 | Interleukin-1 receptor associated kinase | JHX11901 | Diffused Large B-cell Lymphoma | JH X 119 01 | macroglobulinemia
相关产品: Zabedosertib | IRAK4-IN-7 | IRAK4-IN-4 | GLPG2534 | CA-4948 | PROTAC IRAK4 degrader-8 | IRAK4-IN-24 | IRAK4-IN-28 | Larotinib | IRAK-1-4 Inhibitor I
相关库: Anti-Prostate Cancer Compound Library | Anti-Liver Cancer Compound Library | Pyroptosis Compound Library | Anti-Cancer Compound Library | NF-κB Signaling Compound Library | Bioactive Compounds Library Max | Anti-Ovarian Cancer Compound Library | Inhibitor Library | Kinase Inhibitor Library | Bioactive Compound Library
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途