化合物BAY 2666605 T9805
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
100 mg | 2275774-60-0 | ¥11,600.00 | 询底价 |
25 mg | 2275774-60-0 | ¥6,390.00 | 询底价 |
5 mg | 2275774-60-0 | ¥2,490.00 | 询底价 |
50 mg | 2275774-60-0 | ¥8,630.00 | 询底价 |
10 mg | 2275774-60-0 | ¥3,970.00 | 询底价 |
1 mL | 2275774-60-0 | ¥2,730.00 | 询底价 |
1 mg | 2275774-60-0 | ¥1,220.00 | 询底价 |
Product Introduction
Bioactivity
英文名: BAY 2666605
描述: BAY 2666605 是一种具有口服活性的 PDE3A 和 PDE3B 抑制剂,IC50 分别为 87 nM 和 50 nM。 BAY 2666605 具有抗癌作用。
体外活性: BAY 2666605 inhibits brain cancer(glioma, more specifically glioblastoma, astrocytoma), breast cancer (ductal carcinoma and adenocarcinoma), cervical cancer, AML(erythroleukemia), lung cancer(NSCLC adenocarcinoma and SCLC), skin cancer(melanoma), esophagus cancer (squamous cell carcinoma), ovarian cancer, (teratocarcinoma, adenocarcinoma), pancreas cancer and prostatic cancer[1].
体内活性: In murine xenotransplantation models of human cancer, BAY 2666605 (5 mg/kg; p.o) exhibits anti-tumor efficacy[1].
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO : 245 mg/mL (695.47 mM)
关键字: anticancer effect | inhibit | orally active | BAY-2666605 | PDE3A-SLFN12 Complex | BAY 2666605 | Phosphodiesterase (PDE) | BAY2666605 | Inhibitor
相关产品: Tiflucarbine | Deltarasin | Levosimendan | NSP-805 | Indomethacin | BRL-50481 | MBCQ | D159687 | PDE9-IN-1 | BAY 73-6691
相关库: Drug Repurposing Compound Library | Anti-Cancer Drug Library | Clinical Compound Library | Bioactive Compounds Library Max | Inhibitor Library | Anti-Cancer Clinical Compound Library | Anti-Cancer Active Compound Library | Metabolism Compound Library | Orally Active Compound Library | Bioactive Compound Library
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途