CD27/TNFRSF7, Rhesus macaque, 重组蛋白 (His) TMPJ-00616

Product Introduction
Bioactivity


英文名: CD27/TNFRSF7 Protein, Rhesus macaque, Recombinant (His)

描述: CD27 antigen, also known as CD27L receptor, T-cell activation antigen CD27, T14, S152, Tp55, TNFRSF7 and Tumor necrosis factor receptor for superfamily member 7，belongs to the TNF-receptor superfamily. CD27 is a single-pass type I membrane protein and exists as a homodimer form, containing three TNFR-Cys repeats. CD27 transduces signals that lead to the activation of NF-KappaB and MAPK8/JNK. CD27 is involved in regulating B-cell activation and immunoglobulin synthesis, binding to the ligand CD70. TRAF2 and TRAF5 have been shown to mediate the signaling process of CD27. CD27-binding protein (SIVA), which is a proapoptotic protein, can bind to CD27 and is thought to play a key role in the apoptosis. CD27 is required for generation and long-term maintenance of T cell immunity.

存储条件: Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6~12 month

关键字: CD 27 | CD-27 | T 14 | TNFRSF-7 | T-14 | TNFRSF 7

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途