Flagellin, Salmonella Typhimurium, 重组蛋白 TMPJ-00789
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
1 mg | TMPJ-00789 | ¥16,600.00 | 询底价 |
500 μg | TMPJ-00789 | ¥13,200.00 | 询底价 |
10 μg | TMPJ-00789 | ¥330.00 | 询底价 |
50 μg | TMPJ-00789 | ¥1,020.00 | 询底价 |
Product Introduction
Bioactivity
英文名: Flagellin Protein, Salmonella Typhimurium, Recombinant
描述: Flagellin is the major structural protein monomer of bacterial flagella. Flagellin through binding to its receptor and activation of antigen presenting cells stimulates the innate and adaptive immune responses. Flagellin is used as an effective systemic or mucosal adjuvant to stimulate the immune system. Flagellin is an agonist of Toll-like receptor 5 (TLR5), a pattern recognition receptor (PRR) of the innate immune system expressed on the basolateral surface of intestinal epithelial cells and on the surface of a subset of intestinal dendritic cells. Flagellin is delivered into the cytosol of macrophages by the T3SS-1 of serotype Typhimurium, where it activates the cytosolic interleukin-1 (IL-1) converting enzyme-protease activating factor (IPAF), a nucleotide-binding and oligomerization domain-like receptor (NLR) of the innate immunesystem. Recognition of flagellin by IPAF leads to activation of the inflammasome, followed by proteolytic activation of IL-1 and IL-18.
存储条件: store at low temperatureLyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6~12 month
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途