ST2/IL-1 RL1, Mouse, 重组蛋白 (aa 27-337, His) TMPJ-00850
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
500 μg | TMPJ-00850 | ¥12,100.00 | 询底价 |
50 μg | TMPJ-00850 | ¥1,970.00 | 询底价 |
1 mg | TMPJ-00850 | ¥17,400.00 | 询底价 |
10 μg | TMPJ-00850 | ¥740.00 | 询底价 |
Product Introduction
Bioactivity
英文名: ST2/IL-1 RL1 Protein, Mouse, Recombinant (aa 27-337, His)
描述: ST2, also called IL-1 R4, is an Interleukin-1 receptor family glycoprotein that plays a role in Th2 immune responses. ST2 is expressed on the surface of mast cells, activated Th2 cells, macrophages, and cardiac myocytes. This receptor is very similar to the IL-1 receptor type I and the IL-18 receptor α chain in that ST2 also has three extracellular Ig domains and an intracellular Toll domain. ST2 binds IL-33, enhances inflammatory cytokines by activating nuclear factor-κB (NF-κB) and mitogen activated protein (MAP) kinases. ST2 exists as either a membrane bound form (ST2L) or as a soluble form (sST2). ST2L acts as a transmembrane signalling receptor for IL-33 by mediating the effect of IL-33 on the inflammatory process, while sST2 can suppress IL-33 activity.
存储条件: Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6~12 month
关键字: DER-4 | DER 4
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途