TIM-3/KIM-3/HAVCR2, Human, 重组蛋白 (aa 22-200, His) TMPK-00190

Product Introduction
Bioactivity


英文名: TIM-3/KIM-3/HAVCR2 Protein, Human, Recombinant (aa 22-200, His)

描述: Hepatitis A virus cellular receptor 2 (HAVCR2), also known as T-cell immunoglobulin and mucin-domain containing-3 (TIM-3), is a protein that in humans is encoded by the HAVCR2 gene.TIM3 is an immune checkpoint and together with other inhibitory receptors including programmed cell death protein 1 (PD-1) and lymphocyte activation gene 3 protein (LAG3) mediate the CD8 T-cell exhaustion. TIM3 has also been shown as a CD4 Th1-specific cell surface protein that regulates macrophage activation and enhances the severity of experimental autoimmune encephalomyelitis in mice.

存储条件: Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6~12 month

关键字: HAVCR 2 | FLJ14428 | KIM-3 | TIMD 3 | FLJ-14428 | FLJ 14428 | TIMD3 | CD 366 | CD-366 | HAVCR-2 | KIM 3

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途