HER2/ERBB2, Human, 重组蛋白 (aa 1-195, His) TMPY-04684
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | 价格 | 操作 |
---|---|---|
50 μg | ¥2,260.00 | 询底价 |
100 μg | ¥3,620.00 | 询底价 |
500 μg | ¥11,690.00 | 询底价 |
200 μg | ¥5,770.00 | 询底价 |
Product Introduction
Bioactivity
英文名: HER2/ERBB2 Protein, Human, Recombinant (aa 1-195, His)
描述: Human epidermal growth factor receptor 2 (HER2), also known as ErbB2, NEU, and CD340, is a type I membrane glycoprotein and belongs to the epidermal growth factor (EGF) receptor family. HER2 protein cannot bind growth factors due to the lacking of ligand binding domain of its own and autoinhibited constitutively. However, HER2 forms a heterodimer with other ligand-bound EGF receptor family members, therefore stabilizes ligand binding and enhances kinase-mediated activation of downstream molecules. HER2 plays a key role in development, cell proliferation and differentiation. HER2 gene has been reported to associate with malignancy and a poor prognosis in numerous carcinomas, including breast, prostate, ovarian, lung cancers and so on.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy
存储条件: Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6~12 month
关键字: MLN-19 | CD 340 | CD-340 | HER 2 | ERVWE-1 | TKR-1 | ERVWE 1 | TKR 1
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途