3-邻甲基槲皮素 TN1266

Product Introduction
Bioactivity


英文名: 3-O-Methylquercetin

描述: 3-O-Methylquercetin 是分离自植物Rhamnus nakaharai 的天然产物，可抑制总 cAMP 和cGMP-phosphodiesterase (PDE)。它对PDE1、PDE5、PDE 和PDE4的IC50分别是31.9 μM、86.9 μM、18.6 μM 和1.6 μM。

体外活性: Formulations composed of octyldodecanol, egg lecithin, water (NE) and cetyl trimethyl ammonium bromide (CNE) were obtained by spontaneous emulsification. This procedure yielded monodisperse nanoemulsions exhibiting a mean droplet size of approximately 200-300 nm. Nanoemulsions were further characterized in terms of zeta-potential, surface tension, and morphology by transmission electron microscopy. The amount of flavonoids incorporated into nanoemulsions reached nearly 100% (at 1 mg/mL). The permeation studies were carried out using ear pig skin mounted in Franz diffusion cells[1]

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

关键字: 3OMethylquercetin | Phosphodiesterase (PDE) | inhibit | 3 O Methylquercetin | 3-O-Methylquercetin | Inhibitor

相关产品: Broussonin A | Nosantine racemate | Hydrangenol 8-O-glucoside | Taraxasterol | norbergenin | Cinobufotalin | α-​Chaconine | Apilimod | Ossirene | Bisacurone

相关库: Membrane Protein-targeted Compound Library | GPCR Compound Library | Cuproptosis Compound Library | RO5 Drug-like Natural Product Library

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途