番荔枝碱 TN1393

Product Introduction
Bioactivity


英文名: (-)-Anonaine

描述: (-)-Anonaine 可从木兰科和安妮科的几个物种中提取出来，具有抗疟、抗菌、抗真菌、抗氧化、抗癌、抗抑郁和血管舒张的活性。(-)-Anonaine 通过 Bax 和 caspase 依赖性途径诱导人类宫颈癌（HeLa）细胞的凋亡，诱导 DNA 损伤并抑制人类肺癌 h1299细胞的生长和迁移。

体外活性: (-)-Anonaine (50-200 μM ; 24h ; ) exhibited significant inhibition to cell growth and migration activities on human lung cancer H1299 cells.[1] (-)-Anonaine (10-200 μM) significant nuclear damages of H1299 cells were observed treatment in a comet assay, whereas higher concentrations (6 and 30 mM) of (-)-anonaine concentrations were required to cause DNA damages in an in vitro plasmid cleavage assay.[1]

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 2.65 mg/mL (10 mM)


关键字: ( ) Anonaine | ()Anonaine | Anonaine

相关产品: Silybin B | NPS-1034 | BO-264 | Topotecan hydrochloride | Atezolizumab | AEG 3482 | Pinobanksin 3-(2-methyl)butyrate | MK-2206 dihydrochloride | Domatinostat tosylate | Phenoxodiol

相关库: Anti-Tumor Natural Product Library | Anti-Cancer Compound Library | Selected Plant-Sourced Compound Library | Anti-Parasitic Compound Library | Anti-Cancer Active Compound Library | Traditional Chinese Medicine Monomer Library | Natural Product Library for HTS | Antiparasitic Natural Product Library | Bioactive Compound Library | Anti-infective Natural Product Library

番荔枝碱 TN1393信息由TargetMol中国为您提供，如您想了解更多关于番荔枝碱 TN1393报价、型号、参数等信息，欢迎来电或留言咨询。

注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途