野马追内酯 K TN1631
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
50 mg | 108657-10-9 | ¥37,373.00 | 询底价 |
5 mg | 108657-10-9 | ¥9,228.00 | 询底价 |
1 mg | 108657-10-9 | ¥3,054.00 | 询底价 |
10 mg | 108657-10-9 | ¥13,842.00 | 询底价 |
25 mg | 108657-10-9 | ¥24,915.00 | 询底价 |
Product Introduction
Bioactivity
英文名: Eupalinolide K
描述: Eupalinolide K 是来自野马追的一种倍半萜内酯,是 STAT3抑制剂,可作为迈克尔反应受体。
体外活性: In this study, glutathione (GSH) was employed, and a UPLC-MS screening method was developed to discover MRAs. We screened MRAs which can inhibit STAT3 using a STAT3-dependent reporter system. Six sesquiterpene lactones, including a new compound Eupalinolide O (1), together with five known compounds, Eupalinolide I (2), Eupalinolide K (3), Eupalinolide H (4), Eupalinolide J (5) and Eupalinolide G (6) were isolated. Eupalinolide J was identified as MRA that decreased luciferase activity of STAT3. Preliminary activity assessment showed that Eupalinolide J could inhibit the viability of TNBC cell lines.
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
关键字: Eupalinolide K | inhibit | Inhibitor | STAT
相关产品: Corylifol A | Eriocalyxin B | Myricanone | Cucurbitacin I | Manassantin A | CMD178 TFA | Picroside I | Icaritin | ML115 | Solamargine
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途