秦艽甲素 TN1681
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
1 mg | 439-89-4 | ¥2,298.00 | 询底价 |
Product Introduction
Bioactivity
英文名: Gentianine
描述: Gentianine 是一种有效的 Swertiamarin 衍生物,具有抗糖尿病、抗精神病、抗炎、降血压、利尿等作用,具有被开发成一种安全的降压药物的潜力。
体外活性: Gentianine significantly decreased TLR4, MyD88 and NF-κB expression, as well as NO production and inflammatory cytokines release. Gentianine co-treatment with TLR4 inhibitor, further decreased TLR4, MyD88 and NF-κB expression, NO production, as well as the inflammatory cytokines. Taken together, Gentianine could be used as a potential anti-ischemic stroke agent by suppressing inflammatory responses via TLR4/NF-κB signaling pathway.[2]Treatment with Gentianine significantly increased adipogenesis, which was associated with a significant increase in the mRNA expression of PPAR-γ, GLUT-4 and adiponectin[1]
体内活性: Effect of Gentianine on tMCAO mouse demonstrated that Gentianine significantly ameliorated tMCAO induced ischemic injury by decreasing brain infarct volume and increasing the neurological score and upper limb muscle strength. Meanwhile, Gentianine significantly decreased the release of serum inflammatory cytokines. Machine learning enables that Gentianine might had anti-ischemic stroke effect through the TLR4/NF-κB signaling pathway. [2]
存储条件: store at low temperature,keep away from direct sunlightPowder: -20°C for 3 years | In solvent: -80°C for 1 year
关键字: Gentianine
相关产品: Conduritol A | Dehydroglyasperin C | Grandifloroside | 7,3',4'-Tri-O-methylluteolin | Geraniin | Methylthiouracil | Selinidin | CDC801 | Moracin D | Echinatine
秦艽甲素 TN1681信息由TargetMol中国为您提供,如您想了解更多关于秦艽甲素 TN1681报价、型号、参数等信息,欢迎来电或留言咨询。
注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途